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Author Interviews from Angina.com
Arterioscler Thromb Vasc Biol. 2011;ATVBAHA.111.237271published online before print December 22 2011, doi:10.1161/ATVBAHA.111.237271 |
Ingrid E. Dumitriu, Paramita Baruah, Caroline J. Finlayson, Ian M. Loftus, Ricardo F. Antunes, Pitt Lim, Nicholas Bunce, and Juan Carlos Kaski
Circulation Research. 2012;CIRCRESAHA.111.261933published online before printJanuary 26 2012, doi:10.1161/CIRCRESAHA.111.261933 |
Duttaroy S, Thorell D, Karlsson L, Börjesson M.
Department of Clinical and Molecular Medicine, Sahlgrenska University Hospital, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden.
Scand Cardiovasc J. 2012 Feb;46(1):2-6. doi: 10.3109/14017431.2011.622783
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Ron Blankstein, Waleed Ahmed, Fabian Bamberg, Ian S. Rogers, Christopher Lothar Schlett, Khurram Nasir, Joao Fontes, Ahmed Tawakol, Thomas J. Brady, John T. Nagurney, Udo Hoffmann, and Quynh A. Truong
Circ Cardiovasc Imaging. 2012;CIRCIMAGING.111.969568published online before print February 3 2012, doi:10.1161/CIRCIMAGING.111.969568 |
KRAHN, A. D., HEALEY, J. S., SIMPSON, C. S., CHAUHAN, V. S., BIRNIE, D. H., CHAMPAGNE, J., GARDNER, M., SANATANI, S., CHAKRABARTI, S., YEE, R., SKANES, A. C., LEONG-SIT, P., AHMAD, K., GOLLOB, M. H., KLEIN, G. J., GULA, L. J. and SHELDON, R. S.
(2012), . Journal of Cardiovascular Electrophysiology, 23: 60–66
doi: 10.1111/j.1540-8167.2011.02185.x |
Yogesh Patel, Jeremiah P. Depta, Eric Novak, Michael Yeung, Kory Lavine, Sudeshna Banerjee, C. Huie Lin, Alan Zajarias, Howard I. Kurz, John M. Lasala, Richard G. Bach, Jasvindar Singh
American Journal of Cardiology - 02 February 2012 (10.1016/j.amjcard.2011.11.022) |
Italo Porto, Luca Di Vito, Francesco Burzotta, Giampaolo Niccoli, Carlo Trani, Antonio M. Leone, Luigi M. Biasucci, Rocco Vergallo, Ugo Limbruno,
and Filippo Crea
Circ Cardiovasc Interv. 2012;CIRCINTERVENTIONS.111.965624
published online before print January 31 2012, doi:10.1161/CIRCINTERVENTIONS.111.965624 |
Schmidt M, Jacobsen JB, Lash TL, Bøtker HE, Sørensen HT.
BMJ. 2012 Jan 25;344:e356. doi: 10.1136/bmj.e356. |
Houtgraaf, Jaco H., den Dekker, Wijnand K., van Dalen, Bas M., Springeling, Tirza, de Jong, Renate, van Geuns, Robert J., Geleijnse, Marcel L., Fernandez-Aviles, Francisco, Zijlsta, Felix, Serruys, Patrick W., Duckers, Henricus J.
J Am Coll Cardiol 2012 59: 539-540 |
Robert R West, Dee A Jones Andrew H HendersonHeart doi:10.1136/heartjnl-2011-300302
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Rubin, Jonathan, Matsushita, Kunihiro, Ballantyne, Christie M., Hoogeveen, Ron, Coresh, Josef, Selvin, ElizabethJ Am Coll Cardiol 2012 59: 484-489 |
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Gian Luigi Russo, Idolo Tedesco, Maria Russo, Angelo Cioppa,Maria Grazia Andreassi, and Eugenio Picano
Eur Heart J first published online August 23, 2011 doi:10.1093/eurheartj/ehr263 |
Fabrizio D'Ascenzo, Enrico Cerrato, Giuseppe Biondi-Zoccai, Claudio Moretti,Pierluigi Omedè, Filippo Sciuto, Mario Bollati, Maria Grazia Modena, Fiorenzo Gaita,and Imad Sheiban
Eur Heart J first published online December 20, 2011 doi:10.1093/eurheartj/ehr456 |
Greger Nilsson, Lars Holmberg, Hans Garmo, Olov Duvernoy, Iwar Sjögren, Bo Lagerqvist, and Carl Blomqvist
JCO JCO.2011.34.5900; published online on December 27, 2011; |
Berton G, Cordiano R, Cavuto F, Giacomini G, De Toni R, Palatini P.
Department of Cardiology, Conegliano General Hospital, Conegliano, Italy.
Am J Cardiol. 2012 Jan 3. [Epub ahead of print] |
Nikolsky E, Mehran R, Dangas GD, Yu J, Parise H, Xu K, Pocock SJ, Stone GW.
Rambam Health Care Campus and Technion Israel Institute of Technology, Haifa, Israel; Cardiovascular Research Foundation, New York, New York.
Am J Cardiol. 2011 Dec 21. [Epub ahead of print] |
Eur Heart J first published online January 11, 2012 doi:10.1093/eurheartj/ehr432
2012 doi:10.1093/eurheartj/ehr432
Claes Held, Romaina Iqbal, Scott A. Lear, Annika Rosengren, Shofiqul Islam,James Mathew, and Salim Yusuf |
Abhinav Goyal, John A. Spertus, Kensey Gosch
Lakshmi Venkitachalam, Philip G. Jones,
Greet Van den Berghe, Mikhail Kosiborod
JAMA. 2012;307(2):157-164.doi:10.1001/jama.2011.1967 |
Luis Nombela-Franco, Cristina Daniela Mitroi, Ignacio Fernández Lozano, Arturo García-Touchard, Jorge Toquero Ramos, Victor Castro Urda, Jose Antonio Fernández Diaz, Elena Perez Pereira, Paula Beltrán Correas, Javier Segovia, Gerald S. Werner, Javier Goicolea Ruigomez, and Luis Alonso Pulpón
Circ Arrhythm Electrophysiol. 2011;CIRCEP.111.968008
published online before print December 28 2011
doi:10.1161/CIRCEP.111.968008 |
G.B. John Mancini, Pamela M. Hartigan, Eric R. Bates, Steven P. Sedlis, David J. Maron, John A. Spertus, Daniel S. Berman, William J. Kostuk, Leslee J. Shaw, William S. Weintraub, Koon K. Teo, Marcin Dada, Bernard R. Chaitman,
Robert A. O'Rourke, and William E. Boden
Circ Cardiovasc Interv. 2011;CIRCINTERVENTIONS.110.960062published online before print November 1 2011, doi:10.1161/CIRCINTERVENTIONS.110.960062 |
Anja M. van der Laan, Alexander Hirsch, Lourens F.H.J. Robbers, Robin Nijveldt, Ingrid Lommerse, Ronak Delewi, Pieter A. van der Vleuten, Bart J. Biemond, Jaap Jan Zwaginga, Wim J. van der Giessen, Felix Zijlstra, Albert C. van Rossum, Carlijn Voermans, C. Ellen van der Schoot, Jan J. Piek
American Heart Journal - January 2012 (Vol. 163, Issue 1, Pages 57-65.e2,
DOI: 10.1016/j.ahj.2011.09.002) |
Journal of Interventional Cardiology. 2011
doi: 10.1111/j.1540-8183.2011.00698. SAVIC, L., MRDOVIC, I., PERUNICIC, J., ASANIN, M., LASICA, R., MARINKOVIC, J., VASILJEVIC, Z. and OSTOJIC, M |
Jacob Lønborg, Henning Kelbæk, Niels Vejlstrup, Hans Erik Bøtker, Won Yong Kim, Lene Holmvang, Erik Jørgensen, Steffen Helqvist, Kari Saunamäki, Leif Thuesen,Lars Romer Krusell, Peter Clemmensen, and Thomas Engstrøm
Eur J Echocardiogr first published online December 29, 2011 doi:10.1093/ejechocard/jer296 |
Bakhai A, Ferrieres J, Iñiguez A, Sartral M, Belger M, Schmitt C, Zeymer U.
Barnet & Chase Farm NHS Trust, Barnet, United Kingdom AMORE Health Ltd, London, United Kingdom Department of Cardiology, Toulouse Rangueil University Hospital, Toulouse, France Hospital Meixoeiro, Vigo, Spain Eli Lilly and Company, United Kingdom & France Institut für Herzinfarktforschung, Ludwigshafen, Germany.
J Interv Cardiol. 2011 Dec 8. doi: 10.1111/j.1540-8183.2011.00690.x. |
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E. Leshem-Rubinow, Y. Abramowitz, N. Malov, M. Hadad, M. Tamari, M. Golovner,
A. Roth. Arch Intern Med. 2011 Dec 12;171(22):2056-7. |
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Andreas Böning, Martin Brück
Heart heartjnl-2011-301295
Published Online First: 1 December 2011
doi:10.1136/heartjnl-2011-301295
Heart valve prosthesis selection in patients with end-stage renal disease requiring dialysis: a systematic review and meta-analysis
Heart 2011;0:heartjnl-2011-301295v1-heartjnl-2011-30129
Vincent Chan ,Li Chen, Laura Mesana, Thierry G Mesana, Marc Ruel
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Suzanne V. Arnold, MD, MHA, John A. Spertus, MD, MPH, Fengming Tang, MS Harlan M. Krumholz, MD, SM ,William B. Borden, MD; A. Farmer, MD, PhD; Henry H. Ting, MD, MBA,
Paul S. Chan, MD, MSc
CIRCULATIONAHA.111.038265 Published online before print November 7, 2011
doi: 10.1161/?CIRCULATIONAHA.111.038265
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The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse
Eleonora Mezzaroma, Stefano Toldo, Daniela Farkas, Ignacio M. Seropian,
Benjamin W. Van Tassell, Fadi N. Salloum, Harsha R. Kannan, Angela C. Menna, Norbert F. Voelkel, and Antonio Abbate
PNAS 2011 ; published ahead of print November 21, 2011, doi:10.1073/pnas.1108586108
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Safety and Efficacy of Drug-Eluting Stents in Older Patients With Chronic Kidney Disease
Tsai, Thomas T., Messenger, John C., Brennan, J. Matthew, Patel, Uptal D., Dai, David, Piana, Robert N., Anstrom, Kevin J., Eisenstein, Eric L., Dokholyan, Rachel S., Peterson, Eric D., Douglas, Pamela S.
J Am Coll Cardiol 2011 58: 1859-1869
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Bennett MH, Lehm JP, Jepson N. Hyperbaric oxygen therapy for acute coronary syndrome. Cochrane Database of Systematic Reviews 2011, Issue 8. Art. No.: CD004818. DOI: 10.1002/14651858.CD004818.pub3.
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Erectile dyfunction can improve the effectiveness of the current guidelines for the screening for asymptomatic coronary artery disease in diabetes.
Gazzaruso C, Coppola A, Montalcini T, Valenti C, Garzaniti A, Pelissero G, Salvucci F, Gallotti P, Pujia A, Falcone C, Solerte SB, Giustina A.
Internal Medicine, Diabetes, Endocrine-Metabolic Diseases and Cardiovascular Prevention Unit and the Centre for Applied Clinical Research (Ce.R.C.A.), Clinical Institute "Beato Matteo", Corso Pavia 84, Vigevano, 27029, Pavia, Italy
Endocrine. 2011 Aug 23. [Epub ahead of print]
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Division of Cardiology, Schulich Heart Centre, Sunnybrook Health Sciences Centre, Ontario, Canada; Department of Toronto Health Economics and Technology Assessment (THETA) Collaborative, Ontario, Canada; Department of Medicine, University of Toronto, Ontario, Canada.
Can J Cardiol. 2011 Sep 13.
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Mette Christoffersen, Ruth Frikke-Schmidt, Peter Schnohr, Børge G Nordestgaard, Anne Tybjærg-Hansen,
Department of Clinical Biochemistry KB 3011, Section for Molecular Genetics KB 4111, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, DK-2100 Copenhagen Ø, Denmark
BMJ 2011; 343:d5497 doi: 10.1136/bmj.d5497
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Efficacy of exercise-based cardiac rehabilitation post–myocardial infarction: A systematic review and meta-analysis of randomized controlled trials Patrick R. Lawler, Kristian B. Filion, Mark J. Eisenberg
American Heart Journal - 05 September 2011 (10.1016/j.ahj.2011.07.017)
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Nichols RB, McIntyre WF, Chan S, Scogstad-Stubbs D, Hopman WM, Baranchuk A.
Cardiac Electrophysiology and Pacing, Division of Cardiology, Kingston General Hospital, Queen's University, Kingston, ON, K7L 2V7, Canada.
Clin Res Cardiol. 2011 Sep 9.
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Niccoli G, Sgueglia GA, Cosentino N, Piro M, Toma A, Cataneo L, Fracassi F, Porto I, Leone AM, Burzotta F, Trani C, Crea F.
Catholic University of Sacred Heart, Rome, Italy.
Eur J Cardiovasc Prev Rehabil. 2011 Aug 12
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Author Interview:
Robert E. Eckart, LTC MC, FS, US Army
Sudden Death in Young Adults: An Autopsy-Based Series of a Population Undergoing Active Surveillance
Robert E. Eckart, Eric A. Shry, Allen P. Burke, Jennifer A. McNear, David A. Appel, Laudino M. Castillo-Rojas, Lena Avedissian, Lisa A. Pearse, Robert N. Potter, Ladd Tremaine, Philip J. Gentlesk, Linda Huffer, Stephen S. Reich, William G. Stevenson Department of Defense Cardiovascular Death Registry Group
J Am Coll Cardiol 2011 58: 1254-1261.
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Effect of Metabolic Syndrome on Coronary Artery Stenosis and Plaque Characteristics as Assessed with 64-Detector Row Cardiac CT.
Lim S, Shin H, Lee Y, Won Yoon J, Kang SM, Choi SH, Park KS, Jang HC, Choi SI, Chun EJ.
Departments of Internal Medicine and Radiology, Seoul National University College of Medicine and Seoul National University Bundang Hospital, 300 Gumi-dong, Seongnam City, Gyeonggi-do 463-707, South Korea.
Radiology. 2011 Aug 26.
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Spectre G, Mosseri M, Abdelrahman NM, Briskin E, Bulut A, Loncar S, Varon D, Alcalai R.
Hematology Department and Coagulation Unit, Hadassah Hebrew University Medical Center, Jerusalem, Israel.
Am J Cardiol. 2011 Aug 5.
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- Harlan M. Krumholz, MD, SM;
- Jeph Herrin, PhD;
- Lauren E. Miller, MS;
- Elizabeth E. Drye, MD, SM;
- Shari M. Ling, MD;
- Lein F. Han, PhD;
- Michael T. Rapp, MD, JD;
- Elizabeth H. Bradley, PhD;
- Brahmajee K. Nallamothu, MD, MPH;
- Wato Nsa, MD, PhD;
- Dale W. Bratzler, DO, MPH;
- Jeptha P. Curtis, MD
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Brian B. Koo, MD; Terri Blackwell, MA; Sonia Ancoli-Israel, PhD; Katie L. Stone, PhD; Marcia L. Stefanick, PhD; Susan Redline, MD; for the Osteoporotic Fractures in Men (MrOS) Study Group
CIRCULATIONAHA.111.038968 Published online before print August 22, 2011, doi: 10.1161/?CIRCULATIONAHA.111.038968
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Salisbury AC, Reid KJ, Alexander KP, Masoudi FA, Lai SM, Chan PS, Bach RG, Wang TY, Spertus JA, Kosiborod M.
Arch Intern Med. 2011 Aug 8.
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Burkard T, Kaiser CA, Brunner-La Rocca H, Osswald S, Pfisterer ME, Jeger RV; for the BASKET Investigators.
Cardiology, University Hospital, Basel, Switzerland Cardiology, Maastricht University Hospital Center,
Maastricht, the Netherlands.
J Intern Med. 2011 Jul 5. doi: 10.1111/j.1365-2796.2011.02423.x
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Author Interview : Dr. Siamak Rahman
Phosphorylation of GSK-3β Mediates Intralipid-induced Cardioprotection against Ischemia/Reperfusion Injury.
Rahman S, Li J, Bopassa JC, Umar S, Iorga A, Partownavid P, Eghbali M
* Assistant Clinical Professor, Director of UCLA Acute Pain Service, † Postdoctoral Fellow, ‡ Ph.D. Student, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California. § Assistant Clinical Professor, Associate Director of Ambulatory Surgery Center at UCLA, Los Angeles, California. ? Assistant Professor, Department of Anesthesiology, Division of Molecular Medicine, David Geffen School of Medicine at University of California Los Angeles.
Anesthesiology. 2011 Aug;115(2):242-53.
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- Eloi Marijon, MD;
- Muriel Tafflet, PhD;
- David S. Celermajer, PhD, FRACP;
- Florence Dumas, MD;
- Marie-Cécile Perier, MSc;
- Hazrije Mustafic, MD;
- Jean-François Toussaint, MD, PhD;
- Michel Desnos, MD;
- Michel Rieu, MD;
- Nordine Benameur, MD;
- Jean-Yves Le Heuzey, MD;
- Jean-Philippe Empana, MD, PhD;
- Xavier Jouven, MD, PhD
CIRCULATIONAHA.110.008979 Published online before print July 25, 2011, doi: 10.1161/
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- Soo-Jin Kang, MD;
- Gary S. Mintz, MD;
- Takashi Akasaka, MD, PhD;
- Duk-Woo Park, MD, PhD;
- Jong-Young Lee, MD;
- Won-Jang Kim, MD;
- Seung-Whan Lee, MD, PhD;
- Young-Hak Kim, MD, PhD;
- Cheol Whan Lee, MD, PhD;
- Seong-Wook Park, MD, PhD;
- Seung-Jung Park, MD, PhD
Circulation. 2011; 123: 2954-2963 Published online before print June 6, 2011, doi: 10.1161/?
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- Lawrence D. Lazar, MD;
- Mark J. Pletcher, MD, MPH;
- Pamela G. Coxson, PhD;
- Kirsten Bibbins-Domingo, MD, PhD;
- Lee Goldman, MD, MPH
Circulation. 2011; 124: 146-153 Published online before print June 27, 2011, doi: 10.1161/?
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Recovery From Hospital-Acquired Anemia After Acute Myocardial Infarction and Effect on Outcomes.
Salisbury AC, Kosiborod M, Amin AP, Reid KJ, Alexander KP,
Spertus JA, Masoudi FA.
Saint Luke's Mid America Heart Institute, Kansas City, Missouri; University of Missouri-Kansas City School of Medicine, Kansas City, Missouri.
Am J Cardiol. 2011 Jul 22
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Battistella M, Richardson RM, Bargman JM, Chan CT.
Division of Nephrology, Department of Medicine, University Health Network, Toronto, ON, Canada.
Clin Nephrol. 2011 Aug;76(2):99-103.
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Bavry AA, Khaliq A, Gong Y, Handberg EM, Cooper-Dehoff RM, Pepine CJ.
Department of Medicine, College of Medicine, University of Florida, Gainesville.
Am J Med. 2011 Jul;124(7):614-20.
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Gupta PK, Gupta H, Sundaram A, Kaushik M, Fang X, Miller WJ, Esterbrooks DJ, Hunter CB, Pipinos II, Johanning JM, Lynch TG, Forse RA, Mohiuddin SM, Mooss AN.Department of Surgery.
Circulation. 2011 Jul 5.
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Lee CW, Hwang I, Park CS, Lee H, Park DW, Kang SJ, Lee SW, Kim YH, Park SW, Park SJ.
Department of Medicine, Asan Medical Center, University of Ulsan, Seoul, Korea.
Am J Cardiol. 2011 Jul 2
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Taylor RS, Ashton KE, Moxham T, Hooper L, Ebrahim S.
Cochrane Database of Systematic Reviews 2011, Issue 7. Art.
No.: CD009217. DOI: 10.1002/14651858.CD009217
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Bogaty P, Filion KB, Brophy JM.
BMC Cardiovasc Disord. 2011 Jun 20;11(1):34
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Eur Heart J. 2011 May 23.
Kaffashian S, Dugravot A, Nabi H, Batty GD, Brunner E, Kivimäki M, Singh-Manoux A.
INSERM, U1018, Centre for Research in Epidemiology and Population Health, Hôpital Paul Brousse, Bât 15/16, 16 Avenue Paul Vaillant Couturier, F-94807 VILLEJUIF CEDEX, France.
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Andrew Steptoe,Gerard J. Molloy,Nadine Messerli-Bürgy,Anna Wikman, Gemma Randal,
Linda Perkins-Porras and Juan Carlos Kaski
Eur Heart J (2011) doi: 10.1093/eurheartj/ehr132 |
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Author Interview: Dr. Francesca Crowe, PhD
Fruit and vegetable intake and mortality from ischaemic heart disease: results from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Heart study
Crowe FL, Roddam AW, Key TJ, Appleby PN, Overvad K, Jakobsen MU, Tjønneland A, Hansen L, Boeing H, Weikert C, Linseisen J, Kaaks R, Trichopoulou A, Misirli G, Lagiou P, Sacerdote C, Pala V, Palli D, Tumino R, Panico S, Bueno-de-Mesquita HB, Boer J, van Gils CH, Beulens JW, Barricarte A, Rodríguez L, Larrañaga N, Sánchez MJ, Tormo MJ, Buckland G, Lund E, Hedblad B, Melander O, Jansson JH, Wennberg P, Wareham NJ, Slimani N, Romieu I, Jenab M, Danesh J, Gallo V, Norat T, Riboli E; European Prospective Investigation into Cancer and Nutrition (EPIC)-Heart Study Collaborators.
Eur Heart J. 2011 May;32(10):1235-43.
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Caggegi A, Capodanno D, Capranzano P, Chisari A, Ministeri M, Mangiameli A, Ronsivalle G, Ricca G, Barrano G, Monaco S, Di Salvo ME, Tamburino C.
Am J Cardiol. 2011 May 3
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Adam C. Salisbury, Paul S. Chan, Kensey L. Gosch, Donna M. Buchanan, John A. Spertus
American Journal of Cardiology - 15 April 2011 (Vol. 107, Issue 8, Pages 1105-1110, DOI: 10.1016/j.amjcard.2010.12.005)
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Bina Ahmed, MD, Harold L. Dauerman, MD, Winthrop D. Piper, PhD,John F. Robb, MD,
Peter Verlee, MD,Thomas J. Ryan Jr, MD,David Goldberg, MD, Richard A. Boss Jr, MD,William J. Phillips, MD, Frank Fedele, MD,David Butzel, MD,David J. Malenka, MD and on behalf of the Northern New England Cardiovascular Disease Study
Circ Cardiovasc Qual Outcomes.
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Author Interview: Samuel C. Dudley, MD, PhD
Statin Therapy for the Prevention of Atrial Fibrillation Trial (SToP AF trial)
Negi S, Shukrullah I, Veledar E, Bloom HL, Jones DP, Dudley SC.
J Cardiovasc Electrophysiol. 2011 Apr;22(4):414-9. doi: 10.1111/j.1540-8167.2010.01925.x
Section of Cardiology, University of Illinois at Chicago Jesse Brown VA Medical Center, Chicago, Illinois Division of Cardiology and the Atlanta VA Medical Center Division of Pulmonary, Allergy, and Critical Care Medicine, Emory University School of Medicine, Atlanta, Georgia, USA
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Winkel BG, Holst AG, Theilade J, Kristensen IB, Thomsen JL, Ottesen GL, Bundgaard H, Svendsen JH, Haunsø S, Tfelt-Hansen J.
Eur Heart J. 2011 Apr;32(8):983-990.
The Danish National Research Foundation Centre for Cardiac Arrhythmia (DARC), Copenhagen, Denmark.
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Clinical characteristics, vascular function, and inflammation in women with angina in the absence of coronary atherosclerosis the dallas heart study.
JACC Cardiovasc Imaging. 2011 Jan;4(1):65-73.
Banks K, Puttagunta D, Murphy S, Lo M, McGuire DK, de Lemos JA, Chang AY, Grundy SM, Khera A.
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas; Division of Cardiology, University of Texas Southwestern Medical Center, Dallas, Texas
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Patterns of discharge antiplatelet therapy and late outcomes among 8,582 patients with bleeding during acute coronary syndrome: a pooled analysis from PURSUIT, PARAGON-A, PARAGON-B, and SYNERGY.
American Heart Journal 2010 Dec;160(6):1056-64, 1064.e2.
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Featured Angina| Acute Coronary Syndrome and Heart Disease Interviews
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Author Interview: Claes Held MD
Associate professor at Uppsala Clinical Research Center and the
Cardiology department at Uppsala University Hospital in Sweden
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Publication:
Physical activity levels, ownership of goods promoting sedentary behaviour and risk of myocardial infarction: results of the INTERHEART study
Eur Heart J first published online January 11, 2012 doi:10.1093/eurheartj/ehr432
2012 doi:10.1093/eurheartj/ehr432
Claes Held, Romaina Iqbal, Scott A. Lear, Annika Rosengren, Shofiqul Islam,James Mathew, and Salim Yusuf
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What are the main findings of the study?
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The main findings are he following:
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It is well known that physical inactivity is a risk factor for developing cardiovascular disease.
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Our study shows that being physically active reduces the risk of having a heart attack.
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Older studies have mostly studied people in the developed countries. This study which has a global perspective and includes 52 countries from all continents, shows that physical inactivity reduces the risk also in both low- middle-and high-income countries.
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We also found that ownership of a car and TV was associated with a more than doubled risk of being sedentary and that in low- and middle income the risk for a heart attack was increased with 27 %.
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We can however, not conclude from this study that there is a causal relationship but it is an interesting finding.
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Were any of the findings unexpected?
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We looked at the relationship between physical activity both at work and during leisure time.
A bit surprising was that people with heavy physical labor did not have a reduction in the risk of heart attacks, whereas people with both mild and moderate intensity did.
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What should clinicians and patients take away from this study?
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The main findings above and also that physical activity with duration below the recommended 30 minutes/day does seem to prevent from heart attacks as well although not as much as when you do it according to guidelines.
This may be a comfort to those who are completely sedentary and feel that it would be a too big step to move to the 30 minutes/day right away.
All PA does a good job for the heart as compared to not doing anything at all!
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What recommendations do you have for cardiology health care providers as a result of your study?
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It would be interesting to follow up on the ownership of car and TV and do a prospective study to see if the theory holds true.
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Publication:
Short Telomere Length, Myocardial Infarction, Ischemic Heart Disease, and Early Death
- Maren Weischer, Stig E. Bojesen, Richard M. Cawthon, Jacob J. Freiberg,
Anne Tybjærg-Hansen, and Børge G. Nordestgaard
Arterioscler Thromb Vasc Biol. 2011;ATVBAHA.111.237271published online before print December 22 2011, doi:10.1161/ATVBAHA.111.237271 |
What are the main findings of the study?
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One in four Danes have reduced telomere length, that is, increased cellular ageing, and a 25% increased risk of early death and a 50% increased risk of heart attack.
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Were any of the findings unexpected?
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Yes, previous smaller studies have suggested much larger risk increases for early death and heart attack, while we found more modest risk estimates.
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What should clinicians and patients take away from this study?
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A possible prospect of the study is a simple blood test done by the general practitioner, which will reveal a person’s telomeric length and thereby the cellular wear and age.
If the celluar wear is more than expected by age alone, this could be a "wake-up call" suggesting for the patient that now is maybe the time to stop smoking and lose weight.
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What recommendations do you have for cardiology health care providers as a result of your study?
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We need to know if smoking and obesity is the direct cause of reduced telomeric length and thereby increased cellular wear, and whether decreased telomeric length is a direct cause of heart attack and early death.
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Keywords and tags:
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Angina | Heart Disease Resourses
| Chest Pain
Amazon.com 's Editorial Reviews
Angina: New Ways to Treat
Chronic Chest Pain
Part of the award winning public television series Healthy head
/Healthy Mind. It's one of the scariest medical symptoms for people who are generally healthy: a tightening, painful feeling in the chest known as Angina. In some cases this chest pain can be a serious warning that requires immediate treatment. But for the millions of people with chronic, stable angina the discomfort is something that can be readily managed with a variety of treatments. In this program we take a look at what generally causes angina, what can be done to prevent it and how it can be effectively treated with lifestyle changes, innovative drug therapies and medical procedures.
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Amazon.com Editorial Review:
Philips HeartStart Home Defibrillator (AED)
Be prepared for the unexpected.
When sudden cardiac arrest (SCA) strikes, the electrical system of the heart short circuits, causing the heart to quiver rather than pump in a normal rhythm. It typically results in the abnormal heart rhythm know as ventricular fibrillation (VF). It usually happens without warning and the majority of people have no previously recognized symptoms of heart disease. And it most often happens at home. For the best chance of survival from SCA caused by VF, a defibrillator should be used within 5 minutes. Yet, less than 1 in 20 people survive largely because a defibrillator does not arrive in time.
Just as seat belts or airbags do not save every life in a traffic accident, a defibrillator will not save every person who suffers a sudden cardiac arrest. Yet many lives could be saved if more people could be reached more quickly.
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