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PCI - Angioplasty Studies for Coronary Artery Disease
Obstruction in the coronary arteries, or coronary artery disease is frequently treated with a type of procedure called Percutaneous Coronary Intervention (percutaneous means through the skin, as opposed to 'open heart surgery'). A catheter or tube is inserted into a blood vessel, usually in the groin, and threaded into the affected coronary artery under XRay imaging. The blockages can then be opened or repaired using a stent or balloon.
PCI procedures are also called Angioplasty (angio for blood vessel and plasty for repair).
PCI procedures may be known as PTCA or percutaneous transluminal coronary artery procedures, as transluminal means through the opening of the blood vessel, rather than through the chest).
Yogesh Patel, Jeremiah P. Depta, Eric Novak, Michael Yeung, Kory Lavine, Sudeshna Banerjee, C. Huie Lin, Alan Zajarias, Howard I. Kurz, John M. Lasala, Richard G. Bach, Jasvindar Singh
American Journal of Cardiology - 02 February 2012 (10.1016/j.amjcard.2011.11.022) |
Italo Porto, Luca Di Vito, Francesco Burzotta, Giampaolo Niccoli, Carlo Trani, Antonio M. Leone, Luigi M. Biasucci, Rocco Vergallo, Ugo Limbruno,
and Filippo Crea
Circ Cardiovasc Interv. 2012;CIRCINTERVENTIONS.111.965624
published online before print January 31 2012, doi:10.1161/CIRCINTERVENTIONS.111.965624 |
Journal of Interventional Cardiology. 2011
doi: 10.1111/j.1540-8183.2011.00698. SAVIC, L., MRDOVIC, I., PERUNICIC, J., ASANIN, M., LASICA, R., MARINKOVIC, J., VASILJEVIC, Z. and OSTOJIC, M |
Bakhai A, Ferrieres J, Iñiguez A, Sartral M, Belger M, Schmitt C, Zeymer U.
Barnet & Chase Farm NHS Trust, Barnet, United Kingdom AMORE Health Ltd, London, United Kingdom Department of Cardiology, Toulouse Rangueil University Hospital, Toulouse, France Hospital Meixoeiro, Vigo, Spain Eli Lilly and Company, United Kingdom & France Institut für Herzinfarktforschung, Ludwigshafen, Germany.
J Interv Cardiol. 2011 Dec 8. doi: 10.1111/j.1540-8183.2011.00690.x. |
PCI - Angioplasty - PTCA Studies
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Safety and Efficacy of Drug-Eluting Stents in Older Patients With Chronic Kidney Disease
Tsai, Thomas T., Messenger, John C., Brennan, J. Matthew, Patel, Uptal D., Dai, David, Piana, Robert N., Anstrom, Kevin J., Eisenstein, Eric L., Dokholyan, Rachel S., Peterson, Eric D., Douglas, Pamela S.
J Am Coll Cardiol 2011 58: 1859-1869
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Niccoli G, Sgueglia GA, Cosentino N, Piro M, Toma A, Cataneo L, Fracassi F, Porto I, Leone AM, Burzotta F, Trani C, Crea F.
Catholic University of Sacred Heart, Rome, Italy.
Eur J Cardiovasc Prev Rehabil. 2011 Aug 12
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- Harlan M. Krumholz, MD, SM;
- Jeph Herrin, PhD;
- Lauren E. Miller, MS;
- Elizabeth E. Drye, MD, SM;
- Shari M. Ling, MD;
- Lein F. Han, PhD;
- Michael T. Rapp, MD, JD;
- Elizabeth H. Bradley, PhD;
- Brahmajee K. Nallamothu, MD, MPH;
- Wato Nsa, MD, PhD;
- Dale W. Bratzler, DO, MPH;
- Jeptha P. Curtis, MD
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on Hemodialysis.com
Author Interview Dr. Hitinder S. Gurm
Renal Function-Based Contrast Dosing to Define Safe Limits of Radiographic Contrast Media in Patients Undergoing Percutaneous Coronary Interventions
Hitinder S. Gurm, MD*,*, Simon R. Dixon, MBChB , Dean E. Smith, PhD, MPH*, David Share, MD*, Thomas LaLonde, MD , Adam Greenbaum, MD , Mauro Moscucci, MD, MBA|| BMC2 (Blue Cross Blue Shield of Michigan Cardiovascular Consortium) Registry
* Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan Medical Center, Ann Arbor, Michigan
Department of Cardiovascular Medicine, Beaumont Healthcare, Royal Oak, Michigan
Department of Internal Medicine, St. John Hospital, Detroit, Michigan
Department of Internal Medicine, Henry Ford Hospital, Detroit, Michigan
|| Department of Medicine, University of Miami Medical Center, Miami, Florida
J Am Coll Cardiol, 2011; 58:907-914, doi:10.1016/j.jacc.2011.05.023
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- Soo-Jin Kang, MD;
- Gary S. Mintz, MD;
- Takashi Akasaka, MD, PhD;
- Duk-Woo Park, MD, PhD;
- Jong-Young Lee, MD;
- Won-Jang Kim, MD;
- Seung-Whan Lee, MD, PhD;
- Young-Hak Kim, MD, PhD;
- Cheol Whan Lee, MD, PhD;
- Seong-Wook Park, MD, PhD;
- Seung-Jung Park, MD, PhD
Circulation. 2011; 123: 2954-2963 Published online before print June 6, 2011, doi: 10.1161/?
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JAMA: Patients Often Do Not Receive Optimal Medical Therapy Before and After Percutaneous Coronary Intervention
CHICAGO—Despite guideline-based recommendations that underscore the importance of optimal medical therapy (OMT) for patients with stable coronary heart disease undergoing percutaneous coronary intervention (PCI; procedures such as balloon angioplasty or stent placement used to open narrowed coronary arteries), data from a cardiovascular registry indicate that less than half of these patients are receiving OMT before PCI and approximately one-third are not receiving OMT at discharge following PCI, according to a study in the May 11 issue of JAMA.
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Caggegi A, Capodanno D, Capranzano P, Chisari A, Ministeri M, Mangiameli A, Ronsivalle G, Ricca G, Barrano G, Monaco S, Di Salvo ME, Tamburino C.
Am J Cardiol. 2011 May 3
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Bina Ahmed, MD, Harold L. Dauerman, MD, Winthrop D. Piper, PhD,John F. Robb, MD,
Peter Verlee, MD,Thomas J. Ryan Jr, MD,David Goldberg, MD, Richard A. Boss Jr, MD,William J. Phillips, MD, Frank Fedele, MD,David Butzel, MD,David J. Malenka, MD and on behalf of the Northern New England Cardiovascular Disease Study
Circ Cardiovasc Qual Outcomes.
doi:10.1161/CIRCOUTCOMES.110.957175
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Two-year data promising for drug-eluting stent
Dake M. Presented at: 2011 International Symposium on Endovascular Therapy; Jan. 16-20; Miami Beach.
Patients treated with a drug-eluting stent had improved patency rate at 2 years, as well as patient safety, when compared with percutaneous transluminal angioplasty, according to data from a prospective, randomized trial.
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Circ Cardiovasc Interv. 2010 Oct 5.
Singh M, Holmes DR, Lennon RJ, Rihal CS.
Division of Cardiovascular Diseases, the Division of Biostatistics, Mayo Clinic, Rochester, Minn.
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Circ Cardiovasc Interv. 2010 Aug 24.
Ott I, Schulz S et al; for the REVIVAL-3 Study Investigators.
Deutsches Herzzentrum, 1. Medizinische Klinik rechts der Isar, and Nukearmedizinische Klinik rechts der Isar, Munich, Germany.
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Angioplasty Versus Bypass Surgery for Coronary Artery Disease
(Circulation. 2002;106:e187.)
Andrew D. Michaels, MD; Kanu Chatterjee, MB, FRCP
From the Division of Cardiology, Department of Medicine, University of California at San Francisco Medical Center, San Francisco.
Correspondence to: Kanu Chatterjee, MB, FRCP, Professor of Medicine, Lucie Stern Professor of Cardiology, Chatterjee Center for Cardiac Research, University of California, San Francisco, 505 Parnassus Ave, San Francisco, CA 94143.
Angina.com Editor's note : This is a good overall description of the differences between angioplasty or PCI procedures and Bypass surgery, geared toward patients.
Full PDF download of Angioplasty Versus Bypass Surgery for Coronary Artery Disease here
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Percutaneous Coronary Interventions (previously called Angioplasty, Percutaneous Transluminal Coronary [PTCA], or Balloon Angioplasty)
Featured Angina| Acute Coronary Syndrome and Heart Disease Interviews
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Author Interview: Claes Held MD
Associate professor at Uppsala Clinical Research Center and the
Cardiology department at Uppsala University Hospital in Sweden
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Publication:
Physical activity levels, ownership of goods promoting sedentary behaviour and risk of myocardial infarction: results of the INTERHEART study
Eur Heart J first published online January 11, 2012 doi:10.1093/eurheartj/ehr432
2012 doi:10.1093/eurheartj/ehr432
Claes Held, Romaina Iqbal, Scott A. Lear, Annika Rosengren, Shofiqul Islam,James Mathew, and Salim Yusuf
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What are the main findings of the study?
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The main findings are he following:
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It is well known that physical inactivity is a risk factor for developing cardiovascular disease.
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Our study shows that being physically active reduces the risk of having a heart attack.
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Older studies have mostly studied people in the developed countries. This study which has a global perspective and includes 52 countries from all continents, shows that physical inactivity reduces the risk also in both low- middle-and high-income countries.
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We also found that ownership of a car and TV was associated with a more than doubled risk of being sedentary and that in low- and middle income the risk for a heart attack was increased with 27 %.
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We can however, not conclude from this study that there is a causal relationship but it is an interesting finding.
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Were any of the findings unexpected?
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We looked at the relationship between physical activity both at work and during leisure time.
A bit surprising was that people with heavy physical labor did not have a reduction in the risk of heart attacks, whereas people with both mild and moderate intensity did.
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What should clinicians and patients take away from this study?
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The main findings above and also that physical activity with duration below the recommended 30 minutes/day does seem to prevent from heart attacks as well although not as much as when you do it according to guidelines.
This may be a comfort to those who are completely sedentary and feel that it would be a too big step to move to the 30 minutes/day right away.
All PA does a good job for the heart as compared to not doing anything at all!
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What recommendations do you have for cardiology health care providers as a result of your study?
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It would be interesting to follow up on the ownership of car and TV and do a prospective study to see if the theory holds true.
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Abstract
Background— Despite data showing the benefits of implantable cardioverter-defibrillator (ICD) insertion for primary prevention in populations at risk for sudden death, professional society guidelines recommending primary prevention, and recognition by payers of the clinical value of ICDs in these populations, ICDs for primary prevention remain underused. We sought to determine whether implementing a screening tool would increase appropriate identification of patients showing clinical evidence of ICD benefit and prompt referral to an electrophysiologist for ICD implantation.
Methods and Results— Screening tools were affixed to medical records for patients seen in 2 outpatient cardiology offices that queried ejection fraction and whether referral to an electrophysiologist was made (N=6632).
The number of appropriate referrals in the screening period were compared with analogous data collected before implementation of the screening tool (control period) through retrospective record review (n=3606). Significantly more eligible patients were offered referral during the screening period than during the control period at both sites, 80% (8/10 eligible) versus 33% (5/15) at site 1 (P<0.02) and 100% (44/44) versus 60% (21/35) at site 2 (P<0.001). Of all patients offered referral, 41% (32/78) accepted.
Conclusions— The use of a screening tool increases referral to electrophysiology for patients in whom placement of an ICD confers the benefit of sudden cardiac death primary prevention. Barriers to referral include both physician and patient factors. Verification of these findings on a larger scale as well as studies defining the foundation of these barriers may further improve use of ICDs in patients for whom their mortality benefit is well described.
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Keywords and tags:
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Angina | Heart Disease Resourses
| Chest Pain
Amazon.com 's Editorial Reviews
Angina: New Ways to Treat
Chronic Chest Pain
Part of the award winning public television series Healthy head
/Healthy Mind. It's one of the scariest medical symptoms for people who are generally healthy: a tightening, painful feeling in the chest known as Angina. In some cases this chest pain can be a serious warning that requires immediate treatment. But for the millions of people with chronic, stable angina the discomfort is something that can be readily managed with a variety of treatments. In this program we take a look at what generally causes angina, what can be done to prevent it and how it can be effectively treated with lifestyle changes, innovative drug therapies and medical procedures.
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Amazon.com Editorial Review:
Philips HeartStart Home Defibrillator (AED)
Be prepared for the unexpected.
When sudden cardiac arrest (SCA) strikes, the electrical system of the heart short circuits, causing the heart to quiver rather than pump in a normal rhythm. It typically results in the abnormal heart rhythm know as ventricular fibrillation (VF). It usually happens without warning and the majority of people have no previously recognized symptoms of heart disease. And it most often happens at home. For the best chance of survival from SCA caused by VF, a defibrillator should be used within 5 minutes. Yet, less than 1 in 20 people survive largely because a defibrillator does not arrive in time.
Just as seat belts or airbags do not save every life in a traffic accident, a defibrillator will not save every person who suffers a sudden cardiac arrest. Yet many lives could be saved if more people could be reached more quickly.
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