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  More Angina - Heart Disease Interviews
Author Interview: John W. Nance Jr., M.D
Gender Differences in the Predictive Value of the
Presence, Extent, and Composition of Coronary Atherosclerotic Plaque as Measured by Cardiac CT Angiography
Computed tomography (CT) scans of the heart allow three-dimensional views of cardiac anatomy, including the coronary arteries. View Cardiac CT Images from this Abstract

PCI - Angioplasty Studies for Coronary Artery Disease

Obstruction in the coronary arteries, or coronary artery disease is frequently treated with a type of procedure called Percutaneous Coronary Intervention (percutaneous means through the skin, as opposed to 'open heart surgery'). A catheter or tube is inserted into a blood vessel, usually in the groin, and threaded into the affected coronary artery under XRay imaging. The blockages can then be opened or repaired using a stent or balloon.

PCI procedures are also called Angioplasty (angio for blood vessel and plasty for repair).
PCI procedures may be known as PTCA or percutaneous transluminal coronary artery procedures, as transluminal means through the opening of the blood vessel, rather than through the chest).

Author Interview:Jeremiah P. Depta, M.D.

Long-Term Outcomes With Use of Intravascular Ultrasound for the Treatment of Coronary Bifurcation Lesions

Yogesh Patel, Jeremiah P. Depta, Eric Novak, Michael Yeung, Kory Lavine, Sudeshna Banerjee, C. Huie Lin, Alan Zajarias, Howard I. Kurz, John M. Lasala, Richard G. Bach, Jasvindar Singh 

American Journal of Cardiology - 02 February 2012 (10.1016/j.amjcard.2011.11.022)

Author Interview: Italo Porto, MD, PhD

Predictors of Periprocedural (Type IVa) Myocardial Infarction, as Assessed by Frequency-Domain Optical Coherence Tomography

Italo Porto, Luca Di Vito, Francesco Burzotta, Giampaolo Niccoli, Carlo Trani, Antonio M. Leone, Luigi M. Biasucci, Rocco Vergallo, Ugo Limbruno,
and Filippo Crea
Circ Cardiovasc Interv. 2012;CIRCINTERVENTIONS.111.965624
published online before print January 31 2012, doi:10.1161/CIRCINTERVENTIONS.111.965624

Author Interview: Lidija Savic, MD, PhD

Impact of the Combined Left Ventricular Systolic and Renal Dysfunction on One-Year Outcomes after Primary Percutaneous Coronary Intervention.

Journal of Interventional Cardiology. 2011
 doi: 10.1111/j.1540-8183.2011.00698. SAVIC, L., MRDOVIC, I., PERUNICIC, J., ASANIN, M., LASICA, R., MARINKOVIC, J., VASILJEVIC, Z. and OSTOJIC, M

Author Interview: Dr Ameet Bakhai, MBBS, MD, FRCP, MESH, FESC
Consultant Cardiologist

Clinical Outcomes, Resource Use, and Costs at 1 Year in Patients with Acute Coronary Syndrome Undergoing PCI: Results from the Multinational APTOR Registry.

Bakhai A, Ferrieres J, Iñiguez A, Sartral M, Belger M, Schmitt C, Zeymer U.
Barnet & Chase Farm NHS Trust, Barnet, United Kingdom AMORE Health Ltd, London, United Kingdom Department of Cardiology, Toulouse Rangueil University Hospital, Toulouse, France Hospital Meixoeiro, Vigo, Spain Eli Lilly and Company, United Kingdom & France Institut für Herzinfarktforschung, Ludwigshafen, Germany.
J Interv Cardiol. 2011 Dec 8. doi: 10.1111/j.1540-8183.2011.00690.x.

PCI - Angioplasty - PTCA Studies

Author Interview:J. Dawn Abbott, M.D., F.A.C.C., F.S.C.A.I.

Outcomes of Drug-Eluting Stents for Protected Left Main Coronary Artery Disease (from the Multicenter, United States DEScover Registry).


Leitner J, Vlachos HA, Selzer F, Jamal SM, Kip KE, Williams DO, Abbott JD.
Division of Cardiology, Rhode Island Hospital, Brown University, Providence, Rhode Island.
Am J Cardiol. 2011 Nov 23. [Epub ahead of print]

Author Interview: Dr Mamas A Mamas

Influence of access site selection on PCI-related adverse events in patients with STEMI: meta-analysis of randomised controlled trials.

Mamas MA, Ratib K, Routledge H, Fath-Ordoubadi F, Neyses L,
Louvard Y, Fraser DG, Nolan J.

Heart. 2011 Dec 6. [Epub ahead of print]

Author Interview: Dr. Thomas T. Tsai

Safety and Efficacy of Drug-Eluting Stents in Older Patients With Chronic Kidney Disease

Tsai, Thomas T., Messenger, John C., Brennan, J. Matthew, Patel, Uptal D., Dai, David, Piana, Robert N., Anstrom, Kevin J., Eisenstein, Eric L., Dokholyan, Rachel S., Peterson, Eric D., Douglas, Pamela S.
J Am Coll Cardiol 2011 58: 1859-1869

Author Interview: Giampaolo Niccoli, Md, PhD

Impact of gender on clinical outcomes after mTOR-inhibitor drug-eluting stent implantation in patients with first manifestation of ischaemic heart disease.

Niccoli G, Sgueglia GA, Cosentino N, Piro M, Toma A, Cataneo L, Fracassi F, Porto I, Leone AM, Burzotta F, Trani C, Crea F.
Catholic University of Sacred Heart, Rome, Italy.
Eur J Cardiovasc Prev Rehabil. 2011 Aug 12

Improvements in Door-to-Balloon Time in the United States, 2005 to 2010
doi: 10.1161/?CIRCULATIONAHA.111.044107

  1. Harlan M. Krumholz, MD, SM;
  2. Jeph Herrin, PhD;
  3. Lauren E. Miller, MS;
  4. Elizabeth E. Drye, MD, SM;
  5. Shari M. Ling, MD;
  6. Lein F. Han, PhD;
  7. Michael T. Rapp, MD, JD;
  8. Elizabeth H. Bradley, PhD;
  9. Brahmajee K. Nallamothu, MD, MPH;
  10. Wato Nsa, MD, PhD;
  11. Dale W. Bratzler, DO, MPH;
  12. Jeptha P. Curtis, MD
on Hemodialysis.com
Author Interview Dr. Hitinder S. Gurm

Renal Function-Based Contrast Dosing to Define Safe Limits of Radiographic Contrast Media in Patients Undergoing Percutaneous Coronary Interventions

Hitinder S. Gurm, MD*,*, Simon R. Dixon, MBChB{dagger}, Dean E. Smith, PhD, MPH*, David Share, MD*, Thomas LaLonde, MD{ddagger}, Adam Greenbaum, MD§, Mauro Moscucci, MD, MBA|| BMC2 (Blue Cross Blue Shield of Michigan Cardiovascular Consortium) Registry
* Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan Medical Center, Ann Arbor, Michigan
{dagger}Department of Cardiovascular Medicine, Beaumont Healthcare, Royal Oak, Michigan
{ddagger}Department of Internal Medicine, St. John Hospital, Detroit, Michigan
§Department of Internal Medicine, Henry Ford Hospital, Detroit, Michigan
|| Department of Medicine, University of Miami Medical Center, Miami, Florida
J Am Coll Cardiol, 2011; 58:907-914, doi:10.1016/j.jacc.2011.05.023

Author Interview Dr. Seung-Jung Park MD PhD

Optical Coherence Tomographic Analysis of In-Stent Neoatherosclerosis After Drug–Eluting Stent Implantation

  1. Soo-Jin Kang, MD;
  2. Gary S. Mintz, MD;
  3. Takashi Akasaka, MD, PhD;
  4. Duk-Woo Park, MD, PhD;
  5. Jong-Young Lee, MD;
  6. Won-Jang Kim, MD;
  7. Seung-Whan Lee, MD, PhD;
  8. Young-Hak Kim, MD, PhD;
  9. Cheol Whan Lee, MD, PhD;
  10. Seong-Wook Park, MD, PhD;
  11. Seung-Jung Park, MD, PhD

Circulation. 2011; 123: 2954-2963 Published online before print June 6, 2011, doi: 10.1161/?

Author Interview : Dr. Igor Mrdovic
Predicting 30-day major adverse cardiovascular events after primary
percutaneous coronary intervention. The RISK-PCI score


Mrdovic I, Savic L, Krljanac G, Asanin M, Perunicic J, Lasica R, Marinkovic J, Kocev N, Vasiljevic Z, Ostojic M; International Journal of Cardiology (Jun 2011)

Author Interview: Dr. Michael Lee
Long-term outcomes of elective drug-eluting stenting of the unprotected left main coronary artery in patients with normal left ventricular function


Lee MS, Yang T, Biondi-Zoccai G, Sillano D, Cerrato E, Tarantini G, Xhaxho J, Aragon J, Sheiban I.
Division of Cardiology, UCLA Medical Center, Los Angeles, California. .
Catheter Cardiovasc Interv. 2011 Jun 1;77(7):945-51. doi:10.1002/ccd.22777.

Author Interview: Dr. Robert Chait
Midterm outcomes and quality of life following percutaneous coronary intervention in nonagenarians.


Chait R, Zad O, Ramineni R, Shukla A, Mitchell A.
Am J Cardiol. 2011 Jun 1;107(11):1609-12.
JFK Medical Center, Atlantis, Florida; University of Miami Regional Campus, Miller School of Medicine at Florida Atlantic University, Miami, Florida

Author Interview:  Dr. Angela Koh

Percutaneous Coronary Intervention In Asians- Are There Differences In Clinical Outcome?

Koh AS, Khin LW, Choi LM, Sim LL, Chua TS, Koh TH, Tan JW, Chia S.
BMC Cardiovasc Disord. 2011 May 23;11(1):22.

JAMA: Patients Often Do Not Receive Optimal Medical Therapy Before and After Percutaneous Coronary Intervention

CHICAGO—Despite guideline-based recommendations that underscore the importance of optimal medical therapy (OMT) for patients with stable coronary heart disease undergoing percutaneous coronary intervention (PCI; procedures such as balloon angioplasty or stent placement used to open narrowed coronary arteries), data from a cardiovascular registry indicate that less than half of these patients are receiving OMT before PCI and approximately one-third are not receiving OMT at discharge following PCI, according to a study in the May 11 issue of JAMA.

Author Interview: Dr.Sciahbasi
Evaluation of the “Learning Curve” for Left and Right Radial Approach During Percutaneous Coronary Procedures

Sciahbasi A, Romagnoli E, Trani C, Burzotta F, Pendenza G, Tommasino A, Leone AM, Niccoli G, Porto I, Penco M, Lioy E.
Am J Cardiol. 2011 Apr 29.
UO Cardiologia, Policlinico Casilino - ASL RM B, Rome, Italy.

Author Interview: Dr. Bina Ahmed

Recent Changes in Practice of Elective Percutaneous Coronary Intervention for Stable Angina

Bina Ahmed, MD, Harold L. Dauerman, MD, Winthrop D. Piper, PhD,John F. Robb, MD, Peter Verlee, MD,Thomas J. Ryan Jr, MD,David Goldberg, MD, Richard A. Boss Jr, MD,William J. Phillips, MD, Frank Fedele, MD,David Butzel, MD,David J. Malenka, MD and on behalf of the Northern New England Cardiovascular Disease Study

Circ Cardiovasc Qual Outcomes.
doi:10.1161/CIRCOUTCOMES.110.957175

Two-year data promising for drug-eluting stent

Dake M. Presented at: 2011 International Symposium on Endovascular Therapy; Jan. 16-20; Miami Beach.

Patients treated with a drug-eluting stent had improved patency rate at 2 years, as well as patient safety, when compared with percutaneous transluminal angioplasty, according to data from a prospective, randomized trial.

Development and Validation of Risk Adjustment Models for Long-Term Mortality and Myocardial Infarction Following Percutaneous Coronary Interventions.

Circ Cardiovasc Interv. 2010 Oct 5.

Singh M, Holmes DR, Lennon RJ, Rihal CS.
Division of Cardiovascular Diseases, the Division of Biostatistics, Mayo Clinic, Rochester, Minn.

Percutaneous coronary intervention vs coronary artery bypass grafting in the management of chronic stable angina: A critical appraisal.

J Cardiovasc Dis Res. 2010 Apr;1(2):54-8.

Singh AK
Department of Cardiology, C S M Medical University, Lucknow - 226 003, India.

Erythropoietin in Patients With Acute ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention: A Randomized, Double-Blind Trial.

Circ Cardiovasc Interv. 2010 Aug 24.

Ott I, Schulz S et al; for the REVIVAL-3 Study Investigators.
Deutsches Herzzentrum, 1. Medizinische Klinik rechts der Isar, and Nukearmedizinische Klinik rechts der Isar, Munich, Germany.

Angioplasty Versus Bypass Surgery for Coronary Artery Disease
(Circulation. 2002;106:e187.)
Andrew D. Michaels, MD; Kanu Chatterjee, MB, FRCP
From the Division of Cardiology, Department of Medicine, University of California at San Francisco Medical Center, San Francisco.
Correspondence to: Kanu Chatterjee, MB, FRCP, Professor of Medicine, Lucie Stern Professor of Cardiology, Chatterjee Center for Cardiac Research, University of California, San Francisco, 505 Parnassus Ave, San Francisco, CA 94143.

Angina.com Editor's note : This is a good overall description of the differences between angioplasty or PCI procedures and Bypass surgery, geared toward patients.
Full PDF download of Angioplasty Versus Bypass Surgery for Coronary Artery Disease here

IImproved Clinical Outcomes with Intracoronary Compared to Intravenous Abciximab in Patients with Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention: A Systematic Review and Meta-analysis.
J Invasive Cardiol. 2010 Jun;22(6):278-82.
Hansen PR, Iversen A, Abdulla J.
Department of Cardiology P, Gentofte University Hospital, Niels Andersensvej 65, DK-2900 Hellerup, Denmark. prh@dadlnet.dk.

 

Percutaneous Coronary Interventions (previously called Angioplasty, Percutaneous Transluminal Coronary [PTCA], or Balloon Angioplasty)

 

 

Featured Angina| Acute Coronary Syndrome and Heart Disease Interviews

Author Interview: Claes Held MD

Associate professor at Uppsala Clinical Research Center and the
Cardiology department at Uppsala University Hospital in Sweden

Publication:

Physical activity levels, ownership of goods promoting sedentary behaviour and risk of myocardial infarction: results of the INTERHEART study

Eur Heart J first published online January 11, 2012 doi:10.1093/eurheartj/ehr432
2012 doi:10.1093/eurheartj/ehr432
Claes Held, Romaina Iqbal, Scott A. Lear, Annika Rosengren, Shofiqul Islam,James Mathew, and Salim Yusuf

What are the main findings of the study?

The main findings are he following:

  • It is well known that physical inactivity is a risk factor for developing cardiovascular disease.

  • Our study shows that being physically active reduces the risk of having a heart attack.

  • Older studies have mostly studied people in the developed countries. This study which has a global perspective and includes 52 countries from all continents, shows that physical inactivity reduces the risk also in both low- middle-and high-income countries.

  • We also found that ownership of a car and TV was associated with a more than doubled risk of being sedentary and that in low- and middle income the risk for a heart attack was increased with 27 %.

  • We can however, not conclude from this study that there is a causal relationship but it is an interesting finding.    

Were any of the findings unexpected?

We looked at the relationship between physical activity both at work and during leisure time.

A bit surprising was that people with heavy physical labor did not have a reduction in the risk of heart attacks, whereas people with both mild and moderate intensity did.

What should clinicians and patients take away from this study?

The main findings above and also that physical activity with duration below the recommended 30 minutes/day does seem to prevent from heart attacks as well although not as much as when you do it according to guidelines.

This may be a comfort to those who are completely sedentary and feel that it would be a too big step to move to the 30 minutes/day right away.

All PA does a good job for the heart as compared to not doing anything at all!  

What recommendations do you have for cardiology health care providers as a result of your study?

It would be interesting to follow up on the ownership of car and TV and do a prospective study to see if the theory holds true.

More Author Interview from Angina.com

More on Exercise and Heart Disease

More on Heart Attack Studies

 

Use of a Screening Tool Improves Appropriate Referral to an Electrophysiologist for Implantable Cardioverter-Defibrillators for Primary Prevention of Sudden Cardiac Death

Circulation: Cardiovascular Quality and Outcomes. 2011; 4: 152-156
Laura M. Gravelin, MD, Jennifer Yuhas, BS, Michael Remetz, MD,  Martha Radford, MD,  John Foley, MD and  Rachel Lampert, MD

Abstract

Background— Despite data showing the benefits of implantable cardioverter-defibrillator (ICD) insertion for primary prevention in populations at risk for sudden death, professional society guidelines recommending primary prevention, and recognition by payers of the clinical value of ICDs in these populations, ICDs for primary prevention remain underused. We sought to determine whether implementing a screening tool would increase appropriate identification of patients showing clinical evidence of ICD benefit and prompt referral to an electrophysiologist for ICD implantation.
 
Methods and Results— Screening tools were affixed to medical records for patients seen in 2 outpatient cardiology offices that queried ejection fraction and whether referral to an electrophysiologist was made (N=6632).

The number of appropriate referrals in the screening period were compared with analogous data collected before implementation of the screening tool (control period) through retrospective record review (n=3606). Significantly more eligible patients were offered referral during the screening period than during the control period at both sites, 80% (8/10 eligible) versus 33% (5/15) at site 1 (P<0.02) and 100% (44/44) versus 60% (21/35) at site 2 (P<0.001). Of all patients offered referral, 41% (32/78) accepted.

Conclusions— The use of a screening tool increases referral to electrophysiology for patients in whom placement of an ICD confers the benefit of sudden cardiac death primary prevention. Barriers to referral include both physician and patient factors. Verification of these findings on a larger scale as well as studies defining the foundation of these barriers may further improve use of ICDs in patients for whom their mortality benefit is well described.

More on Cardiac Defibrillators

 

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Angina | Heart Disease Resourses | Chest Pain

Amazon.com 's Editorial Reviews

Angina: New Ways to Treat
Chronic Chest Pain

Part of the award winning public television series Healthy head /Healthy Mind. It's one of the scariest medical symptoms for people who are generally healthy: a tightening, painful feeling in the chest known as Angina. In some cases this chest pain can be a serious warning that requires immediate treatment. But for the millions of people with chronic, stable angina the discomfort is something that can be readily managed with a variety of treatments. In this program we take a look at what generally causes angina, what can be done to prevent it and how it can be effectively treated with lifestyle changes, innovative drug therapies and medical procedures.

Amazon.com Editorial Review:

Philips HeartStart Home Defibrillator (AED)

Be prepared for the unexpected.
When sudden cardiac arrest (SCA) strikes, the electrical system of the heart short circuits, causing the heart to quiver rather than pump in a normal rhythm. It typically results in the abnormal heart rhythm know as ventricular fibrillation (VF). It usually happens without warning and the majority of people have no previously recognized symptoms of heart disease. And it most often happens at home. For the best chance of survival from SCA caused by VF, a defibrillator should be used within 5 minutes. Yet, less than 1 in 20 people survive largely because a defibrillator does not arrive in time.
Just as seat belts or airbags do not save every life in a traffic accident, a defibrillator will not save every person who suffers a sudden cardiac arrest. Yet many lives could be saved if more people could be reached more quickly.

 

 

cardiac defibrillator, heart start defibrillator

Philips HeartStart Home Defibrillator (AED)

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